Text · study · 2026
Differential gene expression in inflamed mucosa of progressed UC patients compared to inflamed mucosa of non-progressed UC patients
Listed in NCBI GEO
A small percentage of ulcerative colitis patients may experience disease progression into colitis-associated colorectal cancer (CA-CRC).
Description
In the clinic, it is challenging to identify these patients. Consequently, all UC patients are followed closely by e.g. annual colonoscopy from eight years of the UC diagnosis.
Although, the progression may still be difficult to discover as the neoplastic mucosa may appear with a flat structure. The need for biomarkers that early in the UC disease course can predict the predisposition to progress into CA-CRC is therefore highly wanted in the clinic. The objective of this gene expression analysis was to identify a set of genes with differential expression in inflamed mucosa of progressed UC patients compared to inflamed mucosa of non-progressed UC patients.
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The gene expression was examined using Agilent SurePrint G3 human gene expression 60K microarray.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE151nnn/GSE151911 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE151911 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA637649 ncbi.nlm.nih.gov/bioproject/PRJNA637649 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE151911 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |