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Raster · study · 2026

Transcriptomic Landscape of Microglia in Mouse Models of Social Dysfunction and Oxytocin-Mediated Recovery

Listed in NCBI GEO

Atypical social behaviors modeling autism spectrum disorder have been observed in various genetic mutants and after embryonic perturbations in mice.

Description

We previously showed selective vulnerability of parvocellular oxytocin (OT) neurons in the paraventricular hypothalamus (PVH) in mice with social deficits following embryonic exposure to valproic acid (VPA). Here, we demonstrate that VPA induces transcriptional abnormalities in PVH microglia.

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Stated by source
Mus musculus · Other
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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31841512 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title