Data · study · 2026
Changes in ovarian granulosa cell chromatin interactions in response to LH surge
Listed in NCBI GEO
Luteinising hormone (LH) surge leads to widespread genomic changes in ovarian granulosa cells, leading to global regulation of genes that are important for ovulation and female reproduction.
Description
While LH-dependent changes in chromatin accessibility, histone modification and transcription factor activation have been previously described, the influence of the LH-surge on three-dimensional chromatin organisation as well as the activation of enhancer regulatory elements remain unknown.
This study aims to characterise the chromatin 3D structure in granulosa cells, from which to determine changes in chromatin-chromatin interactions and enhancer activation in response to the LH-surge.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300455 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300455 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1280971 ncbi.nlm.nih.gov/bioproject/PRJNA1280971 ↗
project · from NCBI GEO
Topics
- Stated by source
- Mus musculus · Other
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE300455 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |