Table · dataset · 2026
Supporting data for "Comparing host response to SARS-CoV and SARS-CoV-2 in normal human bronchial epithelial cells and Syrian hamsters"
Listed in figshare
Description
<p dir="ltr">Differentiated normal human bronchial epithelial cells (NHBE) were infected with SARS-CoV (strain: HK39849) or SARS-CoV-2 (strain: hCoV-19/Hong Kong/VM0001061/ 2020) at an MOI of 0.5 or MOCK-infected with PBS, and were collected at 2h, 6h, 24h, 48h, and 72h post-infection (hpi) to determine viral load and host response by TCID50 and bulk RNA sequencing (RNAseq), respectively. Male Syrian hamsters were intranasally inoculated with 10<sup>5</sup> TCID50 of SARS-CoV, SARS-CoV-2, or PBS.
Nasal turbinates and lungs were collected on 1, 2, and 5 days post-inoculation (dpi) to determine viral load and host response. Gene-set enrichment analysis (GSEA) was used to identify pathways of significant biological functions.</p>
Links
Where it is published
- DOI doi.org/10.25442/hku.33285636.v1 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Computer Science & AI · Earth & Environmental Science · Economics & Finance · Engineering · Humanities · Life Sciences · Medical virology · Medicine & Health · Ocean & Atmospheric Science · Social Science
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 19 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33285636 | 5 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].anzsrc:field:320705 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Medical virology'] |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[modality].local:modality:rna-seq | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |