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Imaging · study · 2026

Meningioma cell reprogramming and microenvironment interactions underlie brain invasion

Listed in NCBI GEO

Meningiomas brain invasion encumbers resection and increases the risk of tumor recurrence, but the molecular mechanisms underlying meningioma brain invasion are poorly understood.

Description

To identify molecular and cellular features of brain-invasive meningiomas, we performed spatial transcriptomic of brain-invasive meningiomas. Our results reveal that meningioma brain invasion is defined by molecular remodeling of tumor cells and functional interactions within the tumor microenvironment.

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Stated by source
Homo sapiens · Other
From keywords
Life Sciences
Inferred from text
Cancer 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29937414 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title