Omics · study · 2026
Transcriptomic profiling of chronic rhinosinusitis with nasal polyps
Listed in NCBI GEO
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous inflammatory disease characterized by diverse immune responses and molecular endotypes.
Description
This study performed bulk RNA sequencing of nasal mucosal tissues from 22 subjects, including 8 healthy controls, 9 eosinophilic CRSwNP (eCRSwNP), and 5 non-eosinophilic CRSwNP (neCRSwNP) patients. Transcriptomic analysis was conducted to characterize inflammatory signatures.
This dataset provides transcriptomic resources for investigating inflammatory heterogeneity in CRSwNP.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338426 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338426 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1494473 ncbi.nlm.nih.gov/bioproject/PRJNA1494473 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Disease 75% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE338426 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |