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Omics · study · 2026

Cell signaling pathways modulation in silica nanoparticle-saturated macrophages

Listed in NCBI GEO

Description

In this study, we studied RAW 264.7 macrophages saturated with silica nanoparticles (SNPs) of different size (50 and 100 nm), porosity (nonporous, mesoporous), density (solid, mesoporous, and hollow), and surface composition (hydrophobicity) at their maximum non-toxic concentrations to study the changes in gene expression, and immune signaling pathways by RNA sequencing, weighted gene co-expression network analysis (WGCNA), Hallmark and KEGG pathway analysis.

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Expression profiling by high throughput sequencing · Mus musculus
From keywords
Life Sciences
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RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31261314 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title