Omics · study · 2026
Fusion gene discovery in single cells with LongFUSE from high throughput long read single cell transcriptomes
Listed in NCBI GEO
High-throughput long-read single cell RNA sequencing enables full-length transcript discovery of thousands of genes in thousands of cells.
Description
Robust computational tools for detecting fusion genes in individual cells remain missing. Here, we report LongFUSE, a new computational tool that employs XOR logic gate for fast and accurate detection of cell-specific fusion genes and their splicing isoforms.
LongFUSE outperformed existing tools in simulation and real data, demonstrating high accuracy and robustness.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310978 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310978 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1367650 ncbi.nlm.nih.gov/bioproject/PRJNA1367650 ↗
project · from NCBI GEO
- PubMed 41648288 pubmed.ncbi.nlm.nih.gov/41648288 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75% · Simulation 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE310978 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[method].local:method:simulation | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |