Omics · study · 2026
Genome-scale methylation data from BA8 cortex samples from controls and schizophrenia patients.
Listed in NCBI GEO
Schizophrenia is a complex disorder with many contributory factors of which evidence for epigenetic mechanisms comes from the observed ~40% discordance rates between monozygotic twins.
Description
DNA methylation is one of the epigenetic marks of the genome that influence gene expression in response to developmental and environmental cues. In order to identify DNA methylation differences between frontal cortices of schizophrenia patients and age- and sex-matched controls, genome-scale methylation data was generated.
Genomic DNA samples from BA8 samples isolated from 30 controls and 22 schizophrenia patients. The data generated will be useful in identifying patient-associated CpG sites or regions through differential methylation analyses.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE280nnn/GSE280053 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280053 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1176032 ncbi.nlm.nih.gov/bioproject/PRJNA1176032 ↗
project · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Methylation profiling by genome tiling array
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE280053 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:methylation-profiling-by-genome-tiling-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |