Data · study · 2026
An analysis of gemcitabine-resistant cholangiocarcinoma cells
Listed in NCBI GEO
Cholangiocarcinoma (CCA) is an aggressive liver bile duct cancer with a poor prognosis.
Description
For advanced CCA patients, Gemcitabine (GEM)-based chemotherapy is the standard treatment. Since there is only a 20-30% response rate for advanced CCA patients, it is a critical issue to counteract GEM resistance (GR).
We selected two GR iCCA sublines (SSP-25-GR and SNU-1196-GR) from the parental cells (SSP-25 and SNU-1196) to determine the transcriptome profile.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE291nnn/GSE291223 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE291223 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1232597 ncbi.nlm.nih.gov/bioproject/PRJNA1232597 ↗
project · from NCBI GEO
- PubMed 42708082 pubmed.ncbi.nlm.nih.gov/42708082 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE291223 | 7 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |