Omics · study · 2026
Aberrant epithelialization: A plausible factor for the development of endometrial polyps [bulk RNA-seq]
Listed in NCBI GEO
Endometrial polyps (EPs) and adjacent endometrial tissues (adENs) were collected from 12 women undergoing hysteroscopic polypectomy to investigate transcriptomic differences underlying EP development.
Description
Bulk RNA sequencing was performed on all samples to compare gene expression between EPs and adENs. Differential expression analysis revealed high overall transcriptional similarity, with a few significantly altered genes (FDR < 0.05), including upregulation of KMT2B and DLEC1 and downregulation of COL9A1 and RAB3C in proliferative-phase EPs.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305280 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305280 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1304980 ncbi.nlm.nih.gov/bioproject/PRJNA1304980 ↗
project · from NCBI GEO
- PubMed 41712676 pubmed.ncbi.nlm.nih.gov/41712676 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305280 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |