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Omics · study · 2026

Immune architecture of the colon in ICI-mediated colitis compared with ulcerative colitis

Listed in NCBI GEO

Despite clinical success of immune checkpoint inhibitors (ICI), many cancer patients experience immune-related adverse events (irAEs).

Description

Among these, ICI-mediated colitis (IC) is prevalent and is associated with a significant burden on patients and healthcare. Despite resemblance to ulcerative colitis (UC) with respect to clinical symptoms and treatment approaches, IC’s specific causes and cellular mechanisms are incompletely understood.

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From keywords
Life Sciences
Inferred from text
Cancer 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33831712 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title