Omics · study · 2026
Transcriptomic Profiling of HRMVPC and HRMEC Co-culture Under Normal and High Glucose Conditions
Listed in NCBI GEO
We investigated the transcriptomic alterations in human retinal microvascular pericytes (HRMVPC-Immortalized) exposed to normal and high glucose conditions, with or without co-culture with human retinal microvascular endothelial cells (HRMEC-Immortalized).
Description
The study aimed to elucidate how glucose levels and endothelial interaction influence pericyte gene expression, providing insights into the cellular mechanisms potentially involved in diabetic retinopathy.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298973 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298973 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1272042 ncbi.nlm.nih.gov/bioproject/PRJNA1272042 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE298973 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |