Text · study · 2026
TET2 affects keratinocytes and psoriatic dermatitis by regulating MECOM and NTRK1 hydroxymethylation
Listed in NCBI GEO
The ten-eleven translocation (TET) family dioxygenases TET2 oxidize 5-methylcytosine (5-mC) to 5-hmC in DNA.
Description
DNA hydroxymethylation is the most crucial epigenetic modifications in the occurrence and development of a variety of skin diseases. The goal is to determine the targets of TET2 knockdown including DNA hydroxymethylation in keratinocytes.
We profiled a number of important signaling pathways and key factors that may be associated with psoriasis hydroxymethylation and may be potential biomarkers for psoriasis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE267nnn/GSE267409 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE267409 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1111450 ncbi.nlm.nih.gov/bioproject/PRJNA1111450 ↗
project · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Methylation profiling by array
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE267409 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:methylation-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |