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Omics · study · 2026

Mitochondrial transfer from astrocytes to endothelial cells reinforces redox homeostasis and barrier integrity in brain arteriovenous malformation

Listed in NCBI GEO

Brain arteriovenous malformation (BAVM) is a high-flow vascular shunt that predisposes to intracranial hemorrhage and represents a leading cause of stroke in young adults.

Description

Somatic mutations in KRAS or BRAF drive endothelial dysfunction and lesion formation, yet the contribution of non-endothelial cells within the neuro-glial-vascular unit remains incompletely understood.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32642113 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title