Omics · study · 2026
Transcriptomic profiling of pancreatic islets in mice with ALIX deletion in PDGFRα⁺ mesenchymal progenitors under high-fat diet feeding
Listed in NCBI GEO
Using mice in which ALIX, a key regulator of small extracellular vesicle (sEV) biogenesis, was selectively deleted in PDGFRα⁺ mesenchymal progenitors (Pα-ALIXKO mice), we performed RNA sequencing of pancreatic islets isolated from control and Pα-ALIXKO mice under high-fat diet feeding.
Description
This dataset enables the analysis of transcriptomic changes in pancreatic islets derived from control and Pα-ALIXKO mice.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE326nnn/GSE326591 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE326591 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1445972 ncbi.nlm.nih.gov/bioproject/PRJNA1445972 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE326591 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |