Omics · study · 2026
Control of Mycobacterium abscessus pulmonary infection requires IFN- γ Induced formation of foam macrophages
Listed in NCBI GEO
To characterize the post infection responses of gene transcription in mice lungs after M. abscessus infection, we performed genome-wide transcriptional profiling analysis on lungs of WT and Rag2_KO mice after M. abscessus infection both in 7 dpi and 35dpi.
Description
The data revealed dynamic changes in lungs over a 35-day infection course. Four ‘‘functional’’ clusters were highlighted, including innate immunity function, adaptive immunity function, anti-microbial responses and inflammation & cell death.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE232nnn/GSE232854 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE232854 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA974071 ncbi.nlm.nih.gov/bioproject/PRJNA974071 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE232854 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |