Omics · study · 2026
NFIX-mediated transcriptional regulation in skeletal muscle cells
Listed in NCBI GEO
Skeletal muscle plays a central role in voluntary movement and possesses remarkable regenerative capacity following injury.
Description
NFIX, a member of the Nuclear Factor I (NFI) family of transcription factors, is essential for skeletal muscle development and regeneration. Despite its increasing importance, the molecular mechanisms by which NFIX mediates transcriptional regulation in skeletal muscle remain unclear.
In this study, we performed siRNA-mediated knockdown of NFIX in human immortalized skeletal muscle cells and conducted RNA-seq analysis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305570 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305570 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1305512 ncbi.nlm.nih.gov/bioproject/PRJNA1305512 ↗
project · from NCBI GEO
- PubMed 41623611 pubmed.ncbi.nlm.nih.gov/41623611 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305570 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |