Omics · study · 2026
The KDM1A and KDM7A lysine demethylases cooperate to regulate androgen receptor function in prostate cancer cells [siKMD1A & siKDM7A]
Listed in NCBI GEO
KDM1A and KDM7A are Androgen Receptor coregulators.
Description
Here siRNAs targeting KDM1A and KDM7A were used to deplete KDM1A and KDM7A in prostate cancer cells and the effect on androgen regulated gene expression and splicing determined.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE194nnn/GSE194280 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE194280 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA800049 ncbi.nlm.nih.gov/bioproject/PRJNA800049 ↗
project · from NCBI GEO
- PubMed 41870972 pubmed.ncbi.nlm.nih.gov/41870972 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE194280 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |