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Omics · study · 2026

A skull bone marrow-glymphatic-brain axis mediates CD8 T cell trafficking and involvement in post-ischemic stroke injury 01

Listed in NCBI GEO

Here, we identify a skull bone marrow (SBM)-glymphatic-brain axis that mediates the trafficking and delivery of cytotoxic CD8 T cells into the ischemic brain parenchyma in human AIS.

Description

Single-cell transcriptomic profiling of patients with AIS identifies the SBM as a dynamically responsive CD8 T cell reservoir that is transcriptionally distinct from peripheral blood.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33111413 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title