Omics · study · 2026
Bulk RNA-seq of CRH neuron_Ctr vs Tumor
Listed in NCBI GEO
Bulk RNA sequencing was performed on fluorescence-activated cell sorting (FACS)-isolated CRH-expressing neurons from the hypothalamus of control and EO771 tumor-bearing mice.
Description
The objective was to determine how breast tumor development influences transcriptional programs in CRH neurons, including acute stress-related signaling, immune-neuroendocrine communication, and downstream pathway alterations. These datasets are intended for differential gene expression analysis, pathway enrichment, and hypothesis generation for future functional validation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE309nnn/GSE309463 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE309463 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1336121 ncbi.nlm.nih.gov/bioproject/PRJNA1336121 ↗
project · from NCBI GEO
- PubMed 41401811 pubmed.ncbi.nlm.nih.gov/41401811 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE309463 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |