Data · study · 2026
Expression data from Insulin Degrading Enzyme-Knocked Down alpha pancreatic cells (mouse)
Listed in NCBI GEO
Insulin-degrading enzyme (IDE) is a protein with proteolytic and non-proteolytic functions that regulates primary cilium.We hypothesize that IDE deficiency alter expression of genes involved in the formation of the primary cilium .
Description
To test this hypothesis we performed microarray studies in mouse alphaTC1.9 cells with a partial deficiency of IDE gene. Results show that IDE knocdown led to regulation of genes involved in cellular functions related to primary cilium.
We used microarrays to explore whether expression of genes related to cilliogenesis is affected by reduced expression of IDE gene in alpha pancreatic cells
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE297nnn/GSE297590 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE297590 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1265227 ncbi.nlm.nih.gov/bioproject/PRJNA1265227 ↗
project · from NCBI GEO
- PubMed 41667949 pubmed.ncbi.nlm.nih.gov/41667949 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE297590 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |