Table · dataset · 2026
Gene Expression Dataset of Tazemetostat-Treated SW-1736 Cells Using the WNT Signaling RT² Profiler PCR Array
Listed in HKU DataHub and figshare and Loughborough Research Repository — shown once because both records carry DOI 10.6084/m9.figshare.34004814.v1
<p dir="ltr">This dataset contains the raw and processed gene expression data generated from SW-1736 anaplastic thyroid cancer cells treated with the EZH2 inhibitor tazemetostat (EPZ-6438).
Description
Gene expression changes in the WNT signaling pathway were evaluated using the Qiagen RT² Profiler PCR Array Human WNT Signaling Pathway (PAHS-043Z) and the Roche LightCycler 480 real-time PCR system. The dataset includes raw Cp values obtained from control SW-1736 cells and cells treated with tazemetostat for 24, 48, and 72 hours, together with the processed gene expression analysis.
Relative gene expression was evaluated using the comparative Ct/Cp (2^-ΔΔCt) method. The deposited files provide the underlying gene expression data supporting the WNT signaling pathway analyses reported in the associated manuscript, “Investigation of the effect of the EZH2 inhibitor Tazemetostat on apoptosis and the WNT signaling pathway in anaplastic thyroid cancer cells."</p>
Links
Where it is published
- DOI doi.org/10.6084/m9.figshare.34004814.v1 ↗
DOI / persistent id · from datahub hku hk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from datahub hku hk
Topics
- From keywords
- Astronomy & Astrophysics · Cell development, proliferation and death · Cell development, proliferation and death · Cell development, proliferation and death · Chemistry · Chemistry · Computer Science & AI · Computer Science & AI · Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science · Economics & Finance · Economics & Finance · Engineering · Engineering · Gene expression · Gene expression · Gene expression · Humanities · Humanities · Life Sciences · Life Sciences · Life Sciences · Materials Science · Mathematics & Statistics · Medicine & Health · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Psychology & Behavioral Science · Signal transduction · Signal transduction · Signal transduction · Social Science · Social Science
- Inferred from text
- Cancer 75%
Provenance · 3 source records, 41 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| HKU DataHub | oai:figshare.com:article/34004814 | 6 d ago | JSON v1 |
| figshare | oai:figshare.com:article/34004814 | 5 d ago | JSON v1 |
| Loughborough Research Repository | oai:figshare.com:article/34004814 | 5 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · datahub hku hk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:field:310102 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Cell development, proliferation and death'] |
| concepts[field].anzsrc:field:310102 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Cell development, proliferation and death'] |
| concepts[field].anzsrc:field:310102 | mapping · datahub hku hk | vocabulary-mapper@1.0.0 | keywords['Cell development, proliferation and death'] |
| concepts[field].anzsrc:field:310111 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Signal transduction'] |
| concepts[field].anzsrc:field:310111 | mapping · datahub hku hk | vocabulary-mapper@1.0.0 | keywords['Signal transduction'] |
| concepts[field].anzsrc:field:310111 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Signal transduction'] |
| concepts[field].anzsrc:field:310505 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Gene expression'] |
| concepts[field].anzsrc:field:310505 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Gene expression'] |
| concepts[field].anzsrc:field:310505 | mapping · datahub hku hk | vocabulary-mapper@1.0.0 | keywords['Gene expression'] |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].local:field:materials-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:mathematics-statistics | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| description | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | /metadata/dc/description |
| license | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | /metadata/dc/rights |
| publication_date | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| title | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | /metadata/dc/title |