NCL Data2026 · dataset
<b>A lactate-fatty acid loop drives prostate cancer bone colonization by mediating metabolic interplay between tumor cells and osteoblasts</b><p dir="ltr">Bone metastases (BoM) develop in 60–90% of men with advanced prostate cancer (PCa) and are associated with a significantly decreased quality of life and 5-fold increased risk of mortality. However, current frontline treatments offer only marginal improvements in survival and symptom management. In this study, we investigated the metabolic landscape of BoM lesions of PCa and found that
ZivaHub + HKU DataHub + DaYta Ya Rona + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue
Original Data for ARHGAP40-Mediated Suppression of ccRCC Progression via the RhoA–PI3K/AKT Axis<p dir="ltr">This dataset provides the original data supporting the investigation of ARHGAP40 in clear cell renal cell carcinoma. The data include bioinformatic analyses, functional assays, xenograft experiments, signaling pathway analyses, and metabolic/redox-related measurements. These files support the findings that ARHGAP40 is downregulated and hypermethylated in ccRCC and functions as a tumor
ZivaHub + HKU DataHub + DaYta Ya Rona + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue
Supplemental Tables<p dir="ltr">Hassan et al Supplemental Tables</p>
ZivaHub + HKU DataHub + DaYta Ya Rona + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue
Supplemental videos S1-S4<p dir="ltr">Hassan et al, supplemental videos S1-S4 plus legends.</p>
ZivaHub + HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue
Data for Omar-Hmeadi et al PNAS 2026<p dir="ltr">Somatostatin secretion from pancreatic δ-cells inhibits nearby α- and β-cells, and tunes the body’s glycemic set-14 point. The role of δ-cells in diabetes remains unclear, in part due to the difficulty separating intrinsic regulation 15 from intra-islet paracrine effects. Here we compared the function of isolated δ-cells of cadaveric non-diabetic and 16 type-2 diabetic donors, by sing
ZivaHub + HKU DataHub + DaYta Ya Rona + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue
Apigenin ovarian cancer<p dir="ltr">Among stromal cells, fibroblasts serve as a major source of TGF-β1, which promotes ovarian cancer cell proliferation. However, TGF-β1-induced growth enhancement requires AKT activation in ovarian cancer cells, either through intrinsic constitutive hyperactivation or external fibroblast-derived factors other than TGF-β1. Furthermore, AKT activation is important for producing or maintai
HKU DataHub + figshare + Loughborough Research Repository2026 · Astronomical catalogue
Gene Expression Dataset of Tazemetostat-Treated SW-1736 Cells Using the WNT Signaling RT² Profiler PCR Array<p dir="ltr">This dataset contains the raw and processed gene expression data generated from SW-1736 anaplastic thyroid cancer cells treated with the EZH2 inhibitor tazemetostat (EPZ-6438). Gene expression changes in the WNT signaling pathway were evaluated using the Qiagen RT² Profiler PCR Array Human WNT Signaling Pathway (PAHS-043Z) and the Roche LightCycler 480 real-time PCR system. The datase
HKU DataHub + figshare + Loughborough Research Repository2026 · Astronomical catalogue
The critical genes for progression of bladder cancer<p dir="ltr">This dataset is used to predict and screen the critical genes regulating cancer progression.</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Supplementary file 1_Targeting the Correa’s cascade of gastric cancer: the potential role of phytochemicals and autophagy modulation.pdf<p>Gastric cancer (GC) development follows a sequential and complex pathophysiological process known as Correa’s cascade, progressing from chronic gastritis (active or inactive) to precancerous lesions (intestinal metaplasia (IM) and dysplasia) and ultimately to adenocarcinoma. Current GC therapies have limited efficacy and high recurrence rates. Autophagy, a cellular self-degradation mechanism th
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Data Sheet 2_Targeting the Correa’s cascade of gastric cancer: the potential role of phytochemicals and autophagy modulation.pdf<p>Gastric cancer (GC) development follows a sequential and complex pathophysiological process known as Correa’s cascade, progressing from chronic gastritis (active or inactive) to precancerous lesions (intestinal metaplasia (IM) and dysplasia) and ultimately to adenocarcinoma. Current GC therapies have limited efficacy and high recurrence rates. Autophagy, a cellular self-degradation mechanism th
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Data Sheet 1_Targeting the Correa’s cascade of gastric cancer: the potential role of phytochemicals and autophagy modulation.pdf<p>Gastric cancer (GC) development follows a sequential and complex pathophysiological process known as Correa’s cascade, progressing from chronic gastritis (active or inactive) to precancerous lesions (intestinal metaplasia (IM) and dysplasia) and ultimately to adenocarcinoma. Current GC therapies have limited efficacy and high recurrence rates. Autophagy, a cellular self-degradation mechanism th
figshare2026 · Astronomical catalogue
Domain Dissolution in Supported Lipid Bilayers Triggered by Unsaturated Phospholipid AdditionSignificant cellular processes, including protein sorting, signal transduction, and pathogen entry, among others, are associated with membrane microdomains, also known as lipid rafts. Lipid rafts, due to their unique biophysical properties compared to their surrounding environment, which stem from their distinct lipid and protein profiles, have garnered interest in methods and techniques that tune
figshare2026 · Astronomical catalogue
Domain Dissolution in Supported Lipid Bilayers Triggered by Unsaturated Phospholipid AdditionSignificant cellular processes, including protein sorting, signal transduction, and pathogen entry, among others, are associated with membrane microdomains, also known as lipid rafts. Lipid rafts, due to their unique biophysical properties compared to their surrounding environment, which stem from their distinct lipid and protein profiles, have garnered interest in methods and techniques that tune
figshare2026 · Astronomical catalogue
Domain Dissolution in Supported Lipid Bilayers Triggered by Unsaturated Phospholipid AdditionSignificant cellular processes, including protein sorting, signal transduction, and pathogen entry, among others, are associated with membrane microdomains, also known as lipid rafts. Lipid rafts, due to their unique biophysical properties compared to their surrounding environment, which stem from their distinct lipid and protein profiles, have garnered interest in methods and techniques that tune
figshare2026 · Astronomical catalogue
Domain Dissolution in Supported Lipid Bilayers Triggered by Unsaturated Phospholipid AdditionSignificant cellular processes, including protein sorting, signal transduction, and pathogen entry, among others, are associated with membrane microdomains, also known as lipid rafts. Lipid rafts, due to their unique biophysical properties compared to their surrounding environment, which stem from their distinct lipid and protein profiles, have garnered interest in methods and techniques that tune
figshare2026 · Astronomical catalogue
raw data<p dir="ltr">wb raw data</p>
figshare2026 · Astronomical catalogue
Domain Dissolution in Supported Lipid Bilayers Triggered by Unsaturated Phospholipid AdditionSignificant cellular processes, including protein sorting, signal transduction, and pathogen entry, among others, are associated with membrane microdomains, also known as lipid rafts. Lipid rafts, due to their unique biophysical properties compared to their surrounding environment, which stem from their distinct lipid and protein profiles, have garnered interest in methods and techniques that tune
figshare2026 · Astronomical catalogue
Domain Dissolution in Supported Lipid Bilayers Triggered by Unsaturated Phospholipid AdditionSignificant cellular processes, including protein sorting, signal transduction, and pathogen entry, among others, are associated with membrane microdomains, also known as lipid rafts. Lipid rafts, due to their unique biophysical properties compared to their surrounding environment, which stem from their distinct lipid and protein profiles, have garnered interest in methods and techniques that tune
ZivaHub + Deakin Research Online + HKU DataHub + DaYta Ya Rona + figshare + Loughborough Research Repository + UP Research Data Repository2025 · Astronomical catalogue
Sirt1 alleviates angiotensin II-induced ferroptosis in renal tubular epithelial cells by regulating SLC7A11<p dir="ltr">the supplementary files</p>
ZivaHub + Deakin Research Online + DMU Figshare2020 · dataset · restricted
Agonist, antagonist and signaling modulators of ABA receptor for agronomic and post-harvest managementAbscisic acid (ABA) is a ubiquitous phytohormone, plays important roles in several physiological processes, including stress adaptation, flowering, seed germination, fruit ripening, and leaf senescence etc. ABA binds with START domain proteins called Pyrabactin Resistance1 (PYR1)/PYR1-like (PYL)/Regulatory Components of ABA Receptors (RCARs) and controls the activity of PP2C phosphatase proteins a