Excel · study · 2026
Deep sequencing of gonadal white adipose tissue (gWAT) from Floxed Control (WT), adipocyte-specific Gα13 knockout (Gα13 AKO), and Gα12/13 double knockout (Gα12/13 DKO; Gα13 AKO combined with global Gα12 deletion) mice
Listed in NCBI GEO
The therapeutic relevance of GPCR-targeting drugs has expanded, yet the function of Gα12/13 in adipose tissue remain incompletely understood.
Description
This study investigated the metabolic roles of Gα12/13 in adipocytes under conditions of diet-induced obesity. Transcriptomic profiling was performed on gonadal white adipose tissue collected from Floxed Control (WT), adipocyte-specific Gα13 knockout (Gα13 AKO) mice and double knockout mice (Gα12/13 DKO; Gα13 AKO combined with global Gα12 deletion) after 16 weeks of normal chow diet (NCD) or high-fat diet feeding (HFD).
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305870 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305870 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1308073 ncbi.nlm.nih.gov/bioproject/PRJNA1308073 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Sequencing 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305870 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |