Excel · study · 2026
Genetic regulatory axis between AGR2 and ESR1 promotes breast cancer progression
Listed in NCBI GEO
AGR2 has emerged as a key player in tumorigenesis and metastasis, exhibiting upregulation in various types of cancer and contributing to their malignant progression.
Description
Intriguingly, despite its canonical residence within the ER, this enigmatic protein possesses the ability to venture beyond cellular boundaries and manifest tumorigenic properties in the extracellular environment. This study aimed to first define the global transcriptome that is maintained by a functional AGR2 system in breast cancer cells and find potential constituents for this cancer associated process.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE240nnn/GSE240533 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE240533 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1004190 ncbi.nlm.nih.gov/bioproject/PRJNA1004190 ↗
project · from NCBI GEO
- PubMed 42384634 pubmed.ncbi.nlm.nih.gov/42384634 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE240533 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |