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Omics · study · 2026

MYCN reprograms postnatal cells toward embryonic-like transcriptional states and drives tumorigenesis [Neuroblastoma_RNAseq]

Listed in NCBI GEO

This study investigated the transcriptional changes associated with Mycn-induced adrenal tumor development in mice.

Description

RNA sequencing was performed using luciferase-expressing adrenal medulla samples and Mycn-induced adrenal tumors collected at different times after transgene induction. The dataset was generated to characterize early and advanced transcriptional states during Mycn-driven adrenal tumorigenesis.

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Topics

From keywords
Life Sciences
Inferred from text
Cancer 65% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33900212 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title