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Omics · study · 2026

Mouse embryo transcriptomes after two-cell blastomere separation

Listed in NCBI GEO

This study profiled mouse preimplantation embryos by Smart-seq2 RNA-seq to assess whether separation of late two-cell blastomeres alters the developmental transcriptomic program.

Description

The dataset includes control 8-cell embryos, split morula-stage embryos derived from two-cell blastomeres, control morula embryos, split blastocyst-stage embryos derived from two-cell blastomeres, and control blastocysts. The data were used to compare global transcriptomic similarity, developmental-stage effects, sample correlations, hierarchical clustering and pseudotime trajectories between split embryos and intact controls.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32960911 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title