Text · study · 2026
Knee osteoarthritis (OA)-related phenotypes of myeloid-derived suppressor cells (MDSCs) is mediated by infrapatellar fat pad (IPFP)-derived factors in a body mass (BMI)-dependent manner and positively correlates with IPFP-derived adiponectin levels
Listed in NCBI GEO
In osteoarthritis (OA), immune cells including myeloid-derived suppressor cells (MDSCs) infiltrate infrapatellar fat pad.
Description
MDSCs play a crucial role in immune suppression in cancer and autoimmunity, but their function change upon increasing of body mass index (BMI). However, role of MDSC in OA is less studied.
Therefore, this study aimed to investigate the the effect of BMI on gene expression profile in MDSC from knee OA patients.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE292nnn/GSE292129 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE292129 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1237241 ncbi.nlm.nih.gov/bioproject/PRJNA1237241 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE292129 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |