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Omics · study · 2026

Estrogen receptor beta action in mouse granulosa cells in response to LH surge [ERb]

Listed in NCBI GEO

Estrogen signalling is crucial for follicle development, ovulation, ovarian identity maintenance and female fertility.

Description

The canonical pathway for estrogen signalling is through the activation of estrogen receptor alpha (ERa) and beta (ERb), both of which are present in ovarian granulosa cells. To determine the involvement of each estrogen receptor in ovarian functions across folliculogenesis and ovulation, we characterised the chromatin binding profile of ERb and ERb in mouse granulosa cells in response to in vivo LH stimulus.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29976713 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title