Omics · study · 2026
Hes1 regulates bone marrow mesenchymal stromal cell function through suppressing NFATc2-mediated inflammation
Listed in NCBI GEO
Transcriptome analysis reveals that disruption of Hes1 in BM microenvironment alters expression of genes critical for cellular metabolism and inflammation.
Description
Our study unveils a pivotal role of Hes1 in maintaining bone marrow mesenchymal stromal cell hemostasis and regulating their hematopoiesis supportive function.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296738 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296738 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1260980 ncbi.nlm.nih.gov/bioproject/PRJNA1260980 ↗
project · from NCBI GEO
- PubMed 41035406 pubmed.ncbi.nlm.nih.gov/41035406 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE296738 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |