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Single-Tubule RNA-Seq Reveals Signaling regulated by phosphorylated T551/S552 on beta-catenin

Listed in NCBI GEO

Purpose: Experiments were done in WT mice and Mutant (T551A/S552A at beta-catenin) mice.

Description

Cortical collecting ducts (CCD) were manually micro-dissected and utilized for transcriptomic analysis by single-tubule small sample RNA-Seq

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We carried out RNA-sequencing in cortical collecting duct (CCD) from WT and MUT mice. Results and conclusion: RNA-Seq in microdissected CCD showed that cell cycle related genes were significanlty changed in the mutant (T551A/S552A) mice.

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Life Sciences
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RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29107414 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title