Omics · study · 2026
ATAC-seq of liver CD45+ immune cells from naive and Mr BMT mice
Listed in NCBI GEO
Microglia replacement by bone marrow transplantation (Mr BMT) is an emerging strategy for replacing resident macrophages and microglia with donor-derived cells.
Description
To characterize chromatin accessibility changes associated with long-term macrophage replacement, ATAC-seq was performed on liver CD45+ immune cells isolated from 11.5-month-old naïve and Mr BMT mice. This dataset provides genome-wide profiles of accessible chromatin regions in peripheral immune cells following Mr BMT.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE334nnn/GSE334349 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE334349 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1474851 ncbi.nlm.nih.gov/bioproject/PRJNA1474851 ↗
project · from NCBI GEO
- PubMed 42598750 pubmed.ncbi.nlm.nih.gov/42598750 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Genome binding/occupancy profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE334349 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |