Omics · study · 2026
Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling
Listed in NCBI GEO
Bulk RNA-seq was performed on brain tissue from mice following closed head injury (CHI) or sham surgery at 9h, 24h, and 72h post-injury.
Description
Four genotypes were studied: C57BL/6J wild-type, IL-1R1 global knockout (gKO), IL-1R1 endothelial restore (eRestore), and IL-1R1 neuronal restore (nRestore) to dissect cell-type specific IL-1R1 signaling contributions to the transcriptomic response to traumatic brain injury.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE326nnn/GSE326452 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE326452 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1445297 ncbi.nlm.nih.gov/bioproject/PRJNA1445297 ↗
project · from NCBI GEO
- PubMed 42488755 pubmed.ncbi.nlm.nih.gov/42488755 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE326452 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |