Excel · study · 2026
NSUN2 promotes T-ALL cell growth as anRNA m5C methyltransferase
Listed in NCBI GEO
NSUN2 (NOP2/Sun RNA methyltransferase 2), a 5-methylcytosine (m5C) RNA methyltransferase is highly expressed and plays a proto-oncoprotein role in various cancers.
Description
However, the role of NSUN2 in T-ALL remains unknown, we aim to investigate the role of NSUN2 in T-ALL and delineate its underlying mechanism. Then RNA-Seq data were generated with NSUN2-silenced and control (scrambled) Jurkat cells from 3 independent RNA extracts.
The differentially expressed transcripts comparing NSUN2-silenced cells with control cells are displayed.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE276nnn/GSE276394 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE276394 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1157203 ncbi.nlm.nih.gov/bioproject/PRJNA1157203 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE276394 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |