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Omics · study · 2026

Reconstructing the emergence of the human chorion via HIPPO-mediated trophoblast induction: bulk RNA-seq time course

Listed in NCBI GEO

This study investigates how targeted suppression of HIPPO signaling initiates the human trophectoderm program and drives progression toward early chorionic trophoblast and stromal lineages.

Description

This dataset comprises conventional bulk RNA-seq profiles from mTeSR, tHENSM, tHENSM+2i, and days 3, 6, 9, and 12 of HIPPO-mediated trophectoderm induction.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33957914 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title