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Omics · study · 2026

Transcriptomic responses of HAP1 cells to Bu-DIF-3 and CP-DIF-3

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Dictyostelium differentiation-inducing factors (DIFs) and their derivatives regulate diverse cellular functions in mammalian cells, but the molecular responses elicited by individual derivatives remain incompletely understood.

Description

We performed RNA sequencing of HAP1 cells treated for 24 h with vehicle, 5 µM Bu-DIF-3, or 5 µM CP-DIF-3. This dataset enables comparison of the transcriptomic responses to the two DIF-3 derivatives, including stress-response, redox, metabolic, and autophagy-related pathways.

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Expression profiling by high throughput sequencing · Homo sapiens
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Life Sciences
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RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34145614 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title