Omics · study · 2026
Defining transcripts regulated by RBBP4/p300 complex in glioblastoma [RNA-seq]
Listed in NCBI GEO
Purpose: Next-generation sequencing (NGS) has revolutionized the ability to conduct genome wide transcriptional regulation.
Description
The goals of this study was to identify potential genes regulated by RBBP4/p300 complex by comparing transcriptome profiling (RNA-seq) generated in GBM43 expressing control non-targeting shRNA with cells expressing shRNA targeting RBBP4 or p300. Commonly downregulated and upregulated genes by both shRBBP4 and shp300 were considered to potentially be regulated by RBBP4/p300 complex.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE196nnn/GSE196382 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE196382 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA804547 ncbi.nlm.nih.gov/bioproject/PRJNA804547 ↗
project · from NCBI GEO
- PubMed 42291750 pubmed.ncbi.nlm.nih.gov/42291750 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE196382 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |