Excel · study · 2026
Typical plasticisers DEHP, DBP treatment of human liver-like organs
Listed in NCBI GEO
Phthalates are widely used as industrial plasticisers in the manufacture of plastics, resins, rubbers, paints, emulsifiers, medical devices, personal care products, and so on.
Description
Diethylhexyl phthalate (DEHP) and dibutyl phthalate (DBP) are the most common members of the phthalate group. As typical peroxisome proliferators, plasticisers and their derivatives have been shown to induce fatty liver in rodents by interfering with peroxisome proliferator-activated receptors (PPARa) (Feige et al. 2010; Issemann and Green 1990).
In this study, the effects of plasticisers on hepatic glycolipid metabolism were investigated using a human liver organoid to explore the endocrine-disrupting effects of plasticisers and their mechanisms in a state more closely resembling that of a real human organ.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293605 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293605 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1245365 ncbi.nlm.nih.gov/bioproject/PRJNA1245365 ↗
project · from NCBI GEO
- PubMed 41161237 pubmed.ncbi.nlm.nih.gov/41161237 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE293605 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |