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Omics · study · 2026

The Transcriptomic landscape of Kaposi Sarcoma Herpes Virus

Listed in NCBI GEO

Kaposi sarcoma (KS) is a tumor caused by Kaposi sarcoma herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8).

Description

Unlike other virus-associated tumors, where disease progression often continues even after viral eradication, KS requires the persistent presence of KSHV for disease progression. This unique dependency underscores the potential of strategies targeting the virus to also target the tumor.

This study aims to characterize the expression of KSHV viral proteins and identify factors associated with differences in viral gene expression, ultimately formulating treatment targets.

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Topics

From keywords
Life Sciences
Inferred from text
Cancer 65% · Disease 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33403611 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[disease].local:disease:diseaseenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title