Omics · study · 2026
CD37 Impairs Revascularization and Muscle Recovery in Peripheral Artery Disease
Listed in NCBI GEO
Peripheral artery disease (PAD) affects >14 million Americans, and its most severe form, critical limb-threatening ischemia (CLTI), is marked by persistent inflammation and failure of durable skeletal muscle repair.
Description
Tetraspanins organize immune receptor signaling and leukocyte trafficking, but their roles in CLTI remain incompletely defined. Here, we focused on the leukocyte tetraspanin CD37 prompted by transcriptomic evidence of CD37 upregulation in human PAD gastrocnemius muscle.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319430 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319430 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1423274 ncbi.nlm.nih.gov/bioproject/PRJNA1423274 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE319430 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |