Omics · study · 2026
The resin glycoside Cus-1, a cuscutae extract, ameliorates oligozoospermia via an aquaporin-driven p38 MAPK/SAT1/GPX4 axis that suppresses ferroptosis and restores spermatogenesis
Listed in NCBI GEO
This study employed 1H-NMR-guided isolation to rapidly pinpoint, purify and elucidate the on-the-map metabolite resin glycosides“Cus-1” from the Cuscuta chinensis Lam. phenotype, and subsequently interrogated its remedial value in a busulfan (BUS)-induced mouse model of oligozoospermia.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336587 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336587 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1482038 ncbi.nlm.nih.gov/bioproject/PRJNA1482038 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE336587 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |