Data · dataset · 2026
Somatic mutation and clinical follow-up data of an EGFR-mutant NSCLC cohort with TP53 co-mutation
Listed in ScienceDB
This dataset contains data from 222 patients with EGFR-mutant non-small cell lung cancer (NSCLC), generated by targeted next-generation sequencing (a 60-gene panel) of FFPE tumor tissue, together with clinical records and follow-up information.
Description
The dataset includes: EGFR mutation subtype, TP53 co-mutation status, variant allele frequency (VAF), age, sex, smoking history, histological type, clinical stage, treatment regimens, and overall survival (OS).
All data are de-identified; sample IDs were recoded (1, 2, ...), and no personally identifiable information is included. Raw sequencing reads (FASTQ) are held by the testing laboratory and are not publicly available due to patient privacy considerations; they may be obtained from the corresponding author on reasonable request. This dataset supports the analyses in the manuscript "Subtype-specific and dose-dependent prognostic value of TP53 co-mutation in EGFR-mutant non-small cell lung cancer: a retrospective cohort study".
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.012z2 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Medicine & Health · Social Science
- Inferred from text
- Cancer 75% · Longitudinal study 65% · Oncology and carcinogenesis 74% · Sequencing 75%
Provenance · 1 source records, 15 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.012z2 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3211 | enrichment · scidb cn | taxonomy-embedding@1.0.0 | title+keywords+description (74%) |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[method].local:method:longitudinal-study | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/rights |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |