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Data · dataset · 2026

Somatic mutation and clinical follow-up data of an EGFR-mutant NSCLC cohort with TP53 co-mutation

Listed in ScienceDB

This dataset contains data from 222 patients with EGFR-mutant non-small cell lung cancer (NSCLC), generated by targeted next-generation sequencing (a 60-gene panel) of FFPE tumor tissue, together with clinical records and follow-up information.

Description

The dataset includes: EGFR mutation subtype, TP53 co-mutation status, variant allele frequency (VAF), age, sex, smoking history, histological type, clinical stage, treatment regimens, and overall survival (OS).

All data are de-identified; sample IDs were recoded (1, 2, ...), and no personally identifiable information is included. Raw sequencing reads (FASTQ) are held by the testing laboratory and are not publicly available due to patient privacy considerations; they may be obtained from the corresponding author on reasonable request. This dataset supports the analyses in the manuscript "Subtype-specific and dose-dependent prognostic value of TP53 co-mutation in EGFR-mutant non-small cell lung cancer: a retrospective cohort study".

Links

Where it is published

Catalogue records · 1

Topics

Inferred from text
Cancer 75% · Longitudinal study 65% · Oncology and carcinogenesis 74% · Sequencing 75%
Provenance · 1 source records, 15 field assertions
SourceKeyLast seenRaw
ScienceDB10.57760/sciencedb.012z29 d agoJSON v1
FieldAssertionExtractorEvidence
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