ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset
Image_2_Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2.tifIntroduction<p>The emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic. Therapeutic antibodies with potent efficacy to the Omicron variants are urgently demanded.</p>Methods<p>Utilizing the rapid antibody discovery platform, Berkeley Lights Beacon, we isolated two mo
ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset
Image_3_Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2.tifIntroduction<p>The emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic. Therapeutic antibodies with potent efficacy to the Omicron variants are urgently demanded.</p>Methods<p>Utilizing the rapid antibody discovery platform, Berkeley Lights Beacon, we isolated two mo
ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset
Image_4_Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2.tifIntroduction<p>The emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic. Therapeutic antibodies with potent efficacy to the Omicron variants are urgently demanded.</p>Methods<p>Utilizing the rapid antibody discovery platform, Berkeley Lights Beacon, we isolated two mo
ZivaHub + Deakin Research Online + DMU Figshare2026 · dataset
Image_1_Rapid isolation of pan-neutralizing antibodies against Omicron variants from convalescent individuals infected with SARS-CoV-2.tifIntroduction<p>The emergence of SARS-CoV-2 Omicron subvariants has presented a significant challenge to global health, as these variants show resistance to most antibodies developed early in the pandemic. Therapeutic antibodies with potent efficacy to the Omicron variants are urgently demanded.</p>Methods<p>Utilizing the rapid antibody discovery platform, Berkeley Lights Beacon, we isolated two mo
HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Single-cell RNA sequencing
Table2_IDEIS: a tool to identify PTPRC/CD45 isoforms from single-cell transcriptomic data.xlsx<p>Single-cell RNA sequencing (scRNA-seq) methods are widely used in life sciences, including immunology. Typical scRNA-seq analysis pipelines quantify the abundance of particular transcripts without accounting for alternative splicing. However, a well-established pan-leukocyte surface marker, CD45, encoded by the PTPRC gene, presents alternatively spliced variants that define different immune cel
HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Single-cell RNA sequencing
Table1_IDEIS: a tool to identify PTPRC/CD45 isoforms from single-cell transcriptomic data.xlsx<p>Single-cell RNA sequencing (scRNA-seq) methods are widely used in life sciences, including immunology. Typical scRNA-seq analysis pipelines quantify the abundance of particular transcripts without accounting for alternative splicing. However, a well-established pan-leukocyte surface marker, CD45, encoded by the PTPRC gene, presents alternatively spliced variants that define different immune cel
HKU DataHub + figshare + Loughborough Research Repository2026 · Astronomical catalogue
Supporting data for "Human metapneumovirus reprograms macrophage function toward a hybrid antiviral-regulatory state and remodels exosome biology"<p dir="ltr">This repository contains the raw datasets, images, and associated analyses generated in this study evaluating the effect of human metapneumovirus (hMPV) infection on bone marrow-derived macrophages (BMDMs). The repository includes the underlying data associated with both the main and supplementary figures presented in the manuscript. The deposited materials include Excel files contain
HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Single-cell RNA sequencing
DataSheet1_IDEIS: a tool to identify PTPRC/CD45 isoforms from single-cell transcriptomic data.pdf<p>Single-cell RNA sequencing (scRNA-seq) methods are widely used in life sciences, including immunology. Typical scRNA-seq analysis pipelines quantify the abundance of particular transcripts without accounting for alternative splicing. However, a well-established pan-leukocyte surface marker, CD45, encoded by the PTPRC gene, presents alternatively spliced variants that define different immune cel
HKU DataHub + figshare + Loughborough Research Repository2026 · Single-cell RNA sequencing
Multi-omics datasets of human fetal blood and hematopoietic organs<p dir="ltr">This dataset accompanies the study “Atlas of the immune cell development in the human fetal blood”. It includes processed single-cell RNA sequencing data, T-cell and B-cell receptor annotations, flow cytometry data, Olink normalized protein expression (NPX) measurements, single-cell pseudobulk expression data, bulk transcriptomic data from PHA-stimulated peripheral blood mononuclear c
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Pre-existing systemic inflammation modulates acute neuroinflammatory responses following mild traumatic brain injury<p dir="ltr">Raw data for manuscript "Pre-existing systemic inflammation modulates acute neuroinflammatory responses following mild traumatic brain injury"</p>
figshare2026 · Astronomical catalogue
Supporting data for "Metabolic rewiring in CD8+ T cell drives Venetoclax resistance in Acute Myeloid Leukemia"<p dir="ltr">Venetoclax (VEN), in combination with hypomethylating agent, has become the standard of care for unfit and elderly patients with acute myeloid leukemia (AML) but relapse is common. Mechanisms of drug resistance are thought to be intrinsic to leukemic cells. We reported a hitherto undescribed mechanism of venetoclax resistance (VR) pertinent to CD8<sup>+</sup> T cells activity and iden
figshare2026 · Astronomical catalogue
SVG consistently highly ranked in both Vedo CosMx cohort 1 and 2<p dir="ltr">PPI network of highly spatial variable genes consistent in both Vedo CosMx cohort 1 and 2</p>
figshare2026 · Astronomical catalogue
XF_Mdivi.csv<p dir="ltr"> and contain Seahorse extracellular flux data from a number of plates run on a Seahorse XFp analyzer. Cells were pretreated with media or inhibitor and then treated with OxLDL to determine kinetic metabolic responses.</p><p dir="ltr">Column 1 is an auto-generated data point number.</p><p dir="ltr">Column 2 [Measurement] is the sequential measurement number for each assay.</p><p dir="l
figshare2026 · Astronomical catalogue
mtROS_data.csv<p dir="ltr"> contains data from microscopy experiments. Cells were treated with media or OxLDL and stained for mitochondrial reactive oxygen species production. Fluorescence values were recorded in ImageJ and corrected against background.</p><p dir="ltr">Column 1 [ID] is the subject ID number.</p><p dir="ltr">Column 2 [Med] is the corrected fluorescence intensity for media-treated cells.</p><p di
figshare2026 · Astronomical catalogue
OxLDL_Mdivi_qPCR.csv<p dir="ltr"> and contain qPCR data from gene expression experiments. Cells from Seahorse assays were lysed in Trizol and processed for mRNA isolation and reverse transcription to cDNA. Both datasets are similarly structured.</p><p dir="ltr">Column 1 [Sample] is an internal number used for sample storage and location.</p><p dir="ltr">Column 2 [Subj] is a recoded subject number used for pairing in
figshare2026 · Astronomical catalogue
XF_S1QEL.csv<p dir="ltr"> and contain Seahorse extracellular flux data from a number of plates run on a Seahorse XFp analyzer. Cells were pretreated with media or inhibitor and then treated with OxLDL to determine kinetic metabolic responses.</p><p dir="ltr">Column 1 is an auto-generated data point number.</p><p dir="ltr">Column 2 [Measurement] is the sequential measurement number for each assay.</p><p dir="l
figshare2026 · Astronomical catalogue
foam_cell_counts.csv<p dir="ltr"> contains data from microscopy experiments. Cells were treated with DiI-labeled OxLDL in the presence or absence of inhibitor, and counts reflect the number of cells positive for OxLDL.</p><p dir="ltr">Column 1 [ID] is the subject ID number.</p><p dir="ltr">Column 2 [Treat] is the treatment condition. [OxLDL = DiI-OxLDL only; Mdivi = DiI-OxLDL + Mdivi-1]</p><p dir="ltr">Column 3 [Perc
figshare2026 · Astronomical catalogue
OxLDL_S1QEL_qPCR.csv<p dir="ltr"> and contain qPCR data from gene expression experiments. Cells from Seahorse assays were lysed in Trizol and processed for mRNA isolation and reverse transcription to cDNA. Both datasets are similarly structured.</p><p dir="ltr">Column 1 [Sample] is an internal number used for sample storage and location.</p><p dir="ltr">Column 2 [Subj] is a recoded subject number used for pairing in
Teesside University Research Data Repository2020 · dataset
Data for: Impact of dibenzocyclooctadiene lignans from Schisandra chinensis on the redox status and activation of human innate immune system cellsThis dataset includes the cytokine secretion data as concentrations measured from each cell culture supernatant. The data corresponds to Figures 4 and 5 and Table 1 in the manuscript, in which the data is presented as secretion indices calculated from the cytokine concentrations.