Supporting data for "Human metapneumovirus reprograms macrophage function toward a hybrid antiviral-regulatory state and remodels exosome biology"

The repository includes the underlying data associated with both the main and supplementary figures presented in the manuscript. The deposited materials include Excel files containing flow cytometry analyses of BMDMs infected with hMPV (MOI 5) at 24, 48, 72, 96, and 120 hours post-infection, as well as analyses of macrophages treated with conditioned supernatants obtained from hMPV-infected LET-1 cells across a similar infection time course.

The repository also includes RT-qPCR datasets associated with hMPV N gene expression and datasets related to extracellular vesicle and exosome characterization, including transmission electron microscopy (TEM) images, NanoSight nanoparticle tracking analyses, and flow cytometry data. Raw images and experimental data supporting the supplementary analyses are also provided.</p><p dir="ltr">Together, these datasets support the findings regarding macrophage phenotypic reprogramming, antiviral responses, and extracellular vesicle-associated changes induced by hMPV infection.</p>