13 datasets

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">Stem cells and related research and therapy.</p><p dir="ltr"><br></p>

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset contains the raw data associated with Figure 5D of the manuscript.</p>

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>Cancer-associated cadherin 20 (CDH20) is a novel identified cadherin that is genetically altered in several types of human cancer, including cervical cancer. However, its involvement in the progression of cervical cancer remains unknown. In this study, we show that CDH20 was downregulated in clinical cervical cancer samples and its expression correlated with cervical cancer clinical features. C

figshare + Loughborough Research Repository2026 · Astronomical catalogue

Background<p>The survival for many children with relapsed/refractory cancers remains poor despite advances in therapies. Arginine metabolism plays a key role in the pathophysiology of a number of pediatric cancers. We report the first in child study of a recombinant human arginase, BCT-100, in children with relapsed/refractory hematological, solid or CNS cancers.</p>Procedure<p>PARC was a single a

figshare + Loughborough Research Repository2026 · Astronomical catalogue · restricted

<p dir="ltr">This dataset accompanies a study characterising the immune microenvironment of IDH1-mutant intrahepatic cholangiocarcinoma (iCCA). By investigating the impact of the oncometabolite R-2HG on primary murine cells, novel immunotherapeutic strategies for IDH1-mutant iCCA were identified. The repository contains quantitative IDH1 expression data from engineered murine iCCA cell lines, alon

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This study explores the underlying mechanism by which mitochondrial translation supports therapeutic resistance to ivosidenib, which is the targeted therapy for IDH1-mutated intrahepatic cholangiocarcinoma. Using a genome-wide CRISPR library screen in iCCA cells, we identified MTFMT and MTRF1L, mitochondrial translation regulators, as key resistance mechanisms. MTFMT and MTRF1L knockd

figshare2026 · Astronomical catalogue

<p dir="ltr">Dataset includes total four files which corresponding to four chapters (Chapter 2-5) in the thesis. </p><p dir="ltr">Includes fluorescence images, immunoblots images, various biological cellular assays images, NanoSIMS images, antiangiogenetic assay images, cell invasion images, wound-healing images, and LCMS images in jpeg/tif format, easily readable. Includes cryo-EM images in tif f

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

<p dir="ltr">Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancymostly driven by KRASmutations. Emerging RASinhibitors including daraxonrasib exhibit potent therapeutic efficacy against PDAC, yet their efficacy is compromised by acquired resistance. CDKN2A, a pivotal tumor suppressor encoding p16, is frequently inactivated in PDAC. We identify loss of CDKN2A as a determinant of the

figshare2026 · Astronomical catalogue

<p dir="ltr">KRAS, BRCA, and TP53 Mutations as Prognostic Biomarkers in Pancreatic Cancer: A Systematic Review and Meta-Analysis</p><p dir="ltr"><b>1. General Information</b></p><ul><li>Study Title: KRAS, BRCA, and TP53 Mutations as Prognostic Biomarkers in Pancreatic Cancer: A Systematic Review and Meta-Analysis of Survival Outcomes</li><li><b>Corresponding Author:</b> Wahby Mohammed Babaresh</li