8,172 datasets

NCL Data2026 · Sequencing

Introduction<p>Since its first description in 2003, clinical case reports have repeatedly documented that the bacterial species Kerstersia gyiorum is a human pathogen. K. gyiorum has been described in the context of wound and middle ear infections, has been found in urine samples, and has even been recognized as a causative agent of septicemia. However, the pathogenic potential of K. gyiorum canno

NCL Data2026 · dataset

<div><p>Superoxide dismutase 1 (Sod1) is long recognized as a frontline antioxidant, yet its broader role in safeguarding the eukaryotic genome remains under-explored. Here, using a yeast model, we reveal that Sod1 is an indispensable guardian of genomic integrity. Its absence unleashes a genomic storm: whole-genome sequencing uncovered a dramatic surge in single nucleotide variations (13-fold), l

NCL Data2026 · dataset

Background<p>Norovirus GII.17[P17] has re-emerged and has been circulating globally since 2023. In Jiangsu, China, we found that its proportion increased from 2024 onward. Using local surveillance data combined with global sequences, we reconstructed the global spatiotemporal dynamics of GII.17[P17] and explored its evolution and molecular mechanisms.</p>Methods<p>Samples were subjected to whole-g

NCL Data2026 · Sequencing

<p>The West Kallaallit Nunaat (Greenland) coast, characterized by a variety of fjords, bays, and channels influenced by glacier melting and Atlantic and Arctic waters, is one of the most affected ecosystems by climate change. Here, we combine oceanography, optics, microscopy, high throughput sequencing, microalgal strain establishments, and state-of-the-art analytical methods to fully characterize

NCL Data2026 · dataset

<p>Accession numbers for DNA sequencing datasets used in this study.</p>

NCL Data2026 · dataset

Background<p>Norovirus GII.17[P17] has re-emerged and has been circulating globally since 2023. In Jiangsu, China, we found that its proportion increased from 2024 onward. Using local surveillance data combined with global sequences, we reconstructed the global spatiotemporal dynamics of GII.17[P17] and explored its evolution and molecular mechanisms.</p>Methods<p>Samples were subjected to whole-g

NCL Data2026 · Sequencing

<p>The West Kallaallit Nunaat (Greenland) coast, characterized by a variety of fjords, bays, and channels influenced by glacier melting and Atlantic and Arctic waters, is one of the most affected ecosystems by climate change. Here, we combine oceanography, optics, microscopy, high throughput sequencing, microalgal strain establishments, and state-of-the-art analytical methods to fully characterize

NCL Data2026 · dataset

<p dir="ltr">SLO: Datoteka vsebuje preglednico s podatki o sekvenciranju testnih genotipov in rezultatih mapiranja zaporedij na oba haplotipa sorte Apollo.</p><table><tr><td><p dir="ltr">EN: This file contains a table with sequencing data for the test genotypes and sequence-mapping results for both haplotypes of the Apollo cultivar.</p></td></tr></table><p></p>

NCL Data2026 · dataset

<div><p>Superoxide dismutase 1 (Sod1) is long recognized as a frontline antioxidant, yet its broader role in safeguarding the eukaryotic genome remains under-explored. Here, using a yeast model, we reveal that Sod1 is an indispensable guardian of genomic integrity. Its absence unleashes a genomic storm: whole-genome sequencing uncovered a dramatic surge in single nucleotide variations (13-fold), l

NCL Data2026 · dataset

Background<p>Norovirus GII.17[P17] has re-emerged and has been circulating globally since 2023. In Jiangsu, China, we found that its proportion increased from 2024 onward. Using local surveillance data combined with global sequences, we reconstructed the global spatiotemporal dynamics of GII.17[P17] and explored its evolution and molecular mechanisms.</p>Methods<p>Samples were subjected to whole-g

NCL Data2026 · dataset

<div><p>A central challenge in downstream single-cell RNA sequencing (scRNA-seq) analysis is the high-dimensional, small-sample (HDSS) regime, often compounded by class imbalance from rare cell types. These factors hinder robust feature (gene) selection and cell clustering and limit the realism of samples generated by existing simulators. We introduce <i>GARAGE</i>, a <b>G</b>raph-<b>A</b>ttentive

NCL Data2026 · dataset

Background<p>Norovirus GII.17[P17] has re-emerged and has been circulating globally since 2023. In Jiangsu, China, we found that its proportion increased from 2024 onward. Using local surveillance data combined with global sequences, we reconstructed the global spatiotemporal dynamics of GII.17[P17] and explored its evolution and molecular mechanisms.</p>Methods<p>Samples were subjected to whole-g

NCL Data2026 · dataset

<p dir="ltr"><b>ConnecTick project</b> (<i>PID2024-162238NB-100</i>) recognizes the challenges that ticks present as carriers of tickborne pathogens and reservoirs of antibiotic-resistant bacteria (ARBs) and related genes (ARGs). The primary goal of this project is to investigate how the environmental microbiome—comprising host skin and soil microbiomes—affects the composition and diversity of the

NCL Data2026 · dataset

<div><p>Superoxide dismutase 1 (Sod1) is long recognized as a frontline antioxidant, yet its broader role in safeguarding the eukaryotic genome remains under-explored. Here, using a yeast model, we reveal that Sod1 is an indispensable guardian of genomic integrity. Its absence unleashes a genomic storm: whole-genome sequencing uncovered a dramatic surge in single nucleotide variations (13-fold), l

NCL Data2026 · dataset

<div><p>Genomic or transcriptomic sequencing guides the precision of cervical cancer (CC) diagnosis; however, the molecular profile of Asian patients remains poorly understood. We established a comprehensive multi-omics cohort comprising 112 tumor-normal adjacent tissue pairs from Chinese CC patients. Our integrated analysis revealed a mutational burden comparable to other populations, with three

NCL Data2026 · dataset

<div><p>Declining cognitive function in older adults may be linked to reduced nitric oxide (NO) bioavailability, which is supported by oral nitrate-reducing bacteria. Oral microbiome community structure varies geographically, complicating understanding of microbiome-cognition relationships across populations. This study aimed to identify consistent associations between the oral microbiome and cogn

NCL Data2026 · dataset

<div><p>Superoxide dismutase 1 (Sod1) is long recognized as a frontline antioxidant, yet its broader role in safeguarding the eukaryotic genome remains under-explored. Here, using a yeast model, we reveal that Sod1 is an indispensable guardian of genomic integrity. Its absence unleashes a genomic storm: whole-genome sequencing uncovered a dramatic surge in single nucleotide variations (13-fold), l

NCL Data2026 · dataset

<p dir="ltr">The tea tussock moth, Euproctis pseudoconspersa, is an important defoliating pest of tea plants and various economically important crops. However, nuclear genomic resources suitable for investigating chromosome evolution, population genetics, and host adaptation in this species remain limited. In this study, we integrated PacBio HiFi, Hi-C, and Illumina RNA-sequencing data to generate

NCL Data2026 · dataset

<p dir="ltr">1. STUDY OVERVIEW</p><p dir="ltr">Design : Nested case-control study within a retrospective cohortPopulation : Preterm infants born at < 32 weeks of gestationBPD definition : 2018 NICHD criteria (treatment with invasive or non-invasive respiratory support, or supplemental oxygen, at 36 weeks of postmenstrual age); severity grading not appliedMatching : 1:1 on gestational age, birth we

NCL Data2026 · dataset

Background<p>Norovirus GII.17[P17] has re-emerged and has been circulating globally since 2023. In Jiangsu, China, we found that its proportion increased from 2024 onward. Using local surveillance data combined with global sequences, we reconstructed the global spatiotemporal dynamics of GII.17[P17] and explored its evolution and molecular mechanisms.</p>Methods<p>Samples were subjected to whole-g

NCL Data2026 · dataset

<p dir="ltr">SLO: Datoteka vsebuje povzetek podatkov o polimorfizmih SNP za posamezne genotipe, pridobljenih iz datoteke VCF. Namen analize je oceniti kakovost, popolnost in genetsko variabilnost genotipskih podatkov med proučevanimi vzorci.</p><p dir="ltr">Za vsak genotip so prikazani ključni kazalniki, vključno s številom manjkajočih genotipov (missing data) in številom oziroma deležem heterozig

NCL Data2026 · dataset

<div><p>Superoxide dismutase 1 (Sod1) is long recognized as a frontline antioxidant, yet its broader role in safeguarding the eukaryotic genome remains under-explored. Here, using a yeast model, we reveal that Sod1 is an indispensable guardian of genomic integrity. Its absence unleashes a genomic storm: whole-genome sequencing uncovered a dramatic surge in single nucleotide variations (13-fold), l

NCL Data2026 · dataset

<p dir="ltr">SLO: Podatki o sekvenciranju družine WT x BL2/1 in poročilo o poravnavi na oba haplotipa genoma Apollo. Tabela vključuje oznake vzorcev, število sekvenciranih nukleotidov, število sekvenc, število poravnanih odčitkov na haplotip 1 in njihov delež, ter število poravnanih odčitkov na haplotip 2 in njihov delež.</p><p dir="ltr">EN: Sequencing data for the WT x BL2/1 family and mapping re

NCL Data2026 · dataset

Background<p>Norovirus GII.17[P17] has re-emerged and has been circulating globally since 2023. In Jiangsu, China, we found that its proportion increased from 2024 onward. Using local surveillance data combined with global sequences, we reconstructed the global spatiotemporal dynamics of GII.17[P17] and explored its evolution and molecular mechanisms.</p>Methods<p>Samples were subjected to whole-g

NCL Data2026 · Crystal structure

<p>An explicit filtering step to remove chloroplast- and mitochondrial-derived reads was performed. The table includes all amplicon sequence variants (ASVs) detected across internal, external and culture medium samples from the five <i>D. pteronyssinus</i> cultures. For each ASV, the table reports the full taxonomic assignment (from domain to genus), total abundance across all samples, prevalence