Minimal data set for PONE-D-26-35226: passenger co-deletion and glutaminolysis signatures across fourteen cancer types

<p dir="ltr">Tumour-level derived variables underlying the manuscript "Passenger co-deletion confounds glutaminolysis signatures anchored on PTEN loss: a cautionary case for location-aware signature design" (PLOS ONE, PONE-D-26-35226).</p><p dir="ltr">One row per tumour for 6,186 tumours across fourteen TCGA PanCancer Atlas cohorts, carrying PTEN copy-number tier and ordinal severity, PTEN mutation class, per-gene expression z-scores and the glutaminolysis signature score, copy number for the signature genes and 10q23-q24 interval neighbours, consensus tumour purity, per-sample aneuploidy score, microsatellite instability score, tumour mutational burden, ERG expression, a proliferation index, and overall survival.

Includes a data dictionary, the list of seventeen studies assessed but excluded with their tier counts, and SHA-256 checksums.</p><p dir="ltr">No new data were generated. Derived from TCGA PanCancer Atlas expression, copy-number, mutation and clinical data obtained through the cBioPortal datahub, and from the TCGA PanCanAtlas ABSOLUTE consensus purity tables. Primary data are third-party and remain publicly available from those sources.