18 datasets

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset contains the raw data associated with Figure 5D of the manuscript.</p>

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>Cancer-associated cadherin 20 (CDH20) is a novel identified cadherin that is genetically altered in several types of human cancer, including cervical cancer. However, its involvement in the progression of cervical cancer remains unknown. In this study, we show that CDH20 was downregulated in clinical cervical cancer samples and its expression correlated with cervical cancer clinical features. C

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This retrospective, population-based, study evaluates the five-year overall survival rates of a cohort of Soft Tissue Sarcoma (STS) patients as recorded by the Italian high-resolution Veneto Regional Cancer Registry in 2017 and 2018.</p>

figshare + Loughborough Research Repository2026 · Astronomical catalogue

Background<p>The survival for many children with relapsed/refractory cancers remains poor despite advances in therapies. Arginine metabolism plays a key role in the pathophysiology of a number of pediatric cancers. We report the first in child study of a recombinant human arginase, BCT-100, in children with relapsed/refractory hematological, solid or CNS cancers.</p>Procedure<p>PARC was a single a

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset comprises the complete set of experimental results from a study investigating the characterization and functional evaluation of novel anti-LANCL1 monoclonal antibodies, as well as their humanized variants, in hepatocellular carcinoma (HCC) models. The study encompasses a broad range of in vitro and in vivo assays designed to assess antibody specificity, binding affinity,

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset was generated as part of a research project investigating how transfer RNA (tRNA) abundance and tRNA modification regulate codon-dependent translation in hepatocellular carcinoma (HCC). The data cover two complementary aspects of tRNA-mediated translational regulation.</p><p dir="ltr">The first project examines the relationship between transcriptome-derived codon demand a

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This study explores the underlying mechanism by which mitochondrial translation supports therapeutic resistance to ivosidenib, which is the targeted therapy for IDH1-mutated intrahepatic cholangiocarcinoma. Using a genome-wide CRISPR library screen in iCCA cells, we identified MTFMT and MTRF1L, mitochondrial translation regulators, as key resistance mechanisms. MTFMT and MTRF1L knockd

figshare2026 · Astronomical catalogue

<pre><pre>This deposit contains the analysis code, the analysis-ready input data and all<br>derived output tables and figures underlying the study "Co-occurring burden and<br>divergent socioeconomic gradients of bladder and prostate cancer in 49 Asian<br>countries and territories, 1990-2023: an ecological analysis of the Global Burden<br>of Disease Study 2023".<br><br>What the study does. Using th

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

<p>Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment landscape for relapsed and refractory haematological malignancies, producing durable clinical responses in patients with otherwise limited therapeutic options. Despite these advances, significant biological, clinical, and economic barriers continue to limit its broader application, particularly in solid tumours. This l

figshare2026 · Astronomical catalogue

<p>Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment landscape for relapsed and refractory haematological malignancies, producing durable clinical responses in patients with otherwise limited therapeutic options. Despite these advances, significant biological, clinical, and economic barriers continue to limit its broader application, particularly in solid tumours. This l

figshare2026 · Astronomical catalogue

<p>Chimeric antigen receptor (CAR) T-cell therapy has transformed the treatment landscape for relapsed and refractory haematological malignancies, producing durable clinical responses in patients with otherwise limited therapeutic options. Despite these advances, significant biological, clinical, and economic barriers continue to limit its broader application, particularly in solid tumours. This l

figshare2026 · Astronomical catalogue

<p dir="ltr">KRAS, BRCA, and TP53 Mutations as Prognostic Biomarkers in Pancreatic Cancer: A Systematic Review and Meta-Analysis</p><p dir="ltr"><b>1. General Information</b></p><ul><li>Study Title: KRAS, BRCA, and TP53 Mutations as Prognostic Biomarkers in Pancreatic Cancer: A Systematic Review and Meta-Analysis of Survival Outcomes</li><li><b>Corresponding Author:</b> Wahby Mohammed Babaresh</li

figshare2026 · Astronomical catalogue

<p dir="ltr">Tumour-level derived variables underlying the manuscript "Passenger co-deletion confounds glutaminolysis signatures anchored on PTEN loss: a cautionary case for location-aware signature design" (PLOS ONE, PONE-D-26-35226).</p><p dir="ltr">One row per tumour for 6,186 tumours across fourteen TCGA PanCancer Atlas cohorts, carrying PTEN copy-number tier and ordinal severity, PTEN mutatio

figshare2026 · Astronomical catalogue

<p dir="ltr"><b>Background: </b>Glioblastoma (GBM) remains incurable with profound therapeutic resistance. Ferroptosis offers a promising strategy, yet its regulatory mechanisms in GBM are incompletely defined.</p><p dir="ltr"><b>Methods: </b>We evaluated SC‑2001, a STAT3 inhibitor, in GBM cell lines (U251, U-87 MG) and a xenograft model. Ferroptosis was assessed by GSH, ROS, lipid ROS, MDA, and m