Omics · study · 2026
Single-cell RNA sequencing of microglia/macrophages in zebrafish pde6c mutant eyes
Listed in NCBI GEO
We performed single-cell RNA sequencing of microglia/macrophages from eyecups of zebrafish pde6c mutant and their siblings at two time points, 5 days post fertilization and 4 weeks post fertilization using the 10x Genomics platform.
Description
These data allow (i) detailed study of microglia biology and heterogeneity in the zebrafish eye under normal conditions as well as (ii) microglial response to onset of chronic photoreceptor degeneration (5 days post fertilization) and start of Müller glia-mediated regeneration (4 weeks post fertilization) in the pde6c mutant zebrafish.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298347 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298347 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1269003 ncbi.nlm.nih.gov/bioproject/PRJNA1269003 ↗
project · from NCBI GEO
- PubMed 41995141 pubmed.ncbi.nlm.nih.gov/41995141 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Danio rerio · Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75% · Single-cell RNA sequencing 75% · Zoology 71%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE298347 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3109 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (71%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:7955 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |